- Learn how cryo-electron tomography (cryo-ET) provides direct views of macromolecules in their native environment, offering a deeper understanding of cellular organization and function.
- Discover how to convert three-dimensional reconstructions into quantitative models that link molecular structure to cellular mechanisms, enhancing your research capabilities.
- Explore how cryo-ET fits within the growing landscape of nanoscale imaging modalities, including its advantages, challenges, and how it complements other imaging techniques.
Bridging cellular and structural biology through cryo-electron tomography
Free Virtual Event
On Demand
About The Event
Cellular cryo-electron tomography (cryo-ET) holds the grand promise of integrating cellular architecture with molecular structure. Yet, for many cell biologists, this method can seem technically daunting or limited in scope compared to other imaging approaches. In this webinar, Prof. Grotjahn will discuss how cryo-ET is redefining the study of cellular organization by providing direct views of how macromolecules assemble and function in their native environment. Prof. Grotjahn will showcase her lab’s software, Surface Morphometrics, which converts three-dimensional reconstructions into quantitative models linking molecular structure to cellular mechanism. Prof. Grotjahn will highlight where cryo-ET excels, the challenges that remain, and how it fits within the growing landscape of other nanoscale imaging modalities. Explore how these advances are transforming the familiar cartoon models of cells into structural maps of molecular architecture.
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