Workshop Summary:  Speakers will be drawn from the SSRL user community and other global leaders who understand the needs and necessary infrastructures to use cryogenic electron microscopy  to derive structures of targets with drugs or vaccines to address future pandemics or various biological threats.

This will be primarily an in-person workshop, but talks will be available by zoom https://stanford.zoom.us/s/93989304382

LOCATION: SLAC Building 51, Kavli Auditorium

Organizers:  Wah Chiu, Stanford/SLAC/SSRL; Britt Hedman, Stanford/SLAC/SSRL

Invited  Speakers:

1:00 PM – 1:40 PM     Jing Jin, Blood Systems: Integrated analyses reveal how a hinge glycan modulates human coronavirus-NL63  spike tilting and virus infectivity

1:40 PM – 2:20 PM    Christopher Barnes, Stanford University: Structure-guided design of bispecific antibodies that target the       N-terminal and receptor binding domains of the SARS-CoV-2 spike glycoprotein

2:20 PM – 2:35 PM    Break

2:35 PM – 3:15 PM    Peter Kim, Stanford University: A ferritin-nanoparticle COVID-19 vaccine with potential for global accessibility

3:15 PM – 3:55 PM    Rachael Kretsch, Stanford University: Uncovering the structural landscape of viral RNA with cryo-EM

3:55 PM – 4:35 PM    Stephen Burley, Rutgers University: 3D Biostructure Validation in the Protein Data Bank