Fundamentals at SSRL & LCLS Early Career Speaker Award to be presented at the Plenary Session on September 28th to:

• Monty Cosby, SLAC:  Structurally informed in situ X-ray diffraction beamline experiments enabled by real time Rietveld analysis
• Priyanka Muhunthan, Stanford University:  Examining the Structure of Supercritical CO2 from X-ray Raman Spectroscopy, Small Angle X-ray Scattering, and Atomistic Simulations
• Honorable Mention:  Avery Hanna, SLAC:  Maximizing FEL coherence with Hermite-Gaussian modes-based machine learning

Check out the Fundamentals YouTube channel with a growing library of introductory video content about experimental capabilities at SSRL & LCLS.  https://www.youtube.com/@fundamentalsatssrlandlcls8668

Workshop Summary:  Please join in this symposium intended for new and student and postdoc users to learn more about the capabilities and research being conducted at the SLAC User Facilities. This workshop is accompanied by a growing collection of video introductions to the various methods and endstations accessible at SSRL, LCLS, UED, and CryoEM facilities, which can be accessed offline and will increase with new content each year. During the live symposium sessions, expert PhD scientists will introduce crystallography/diffraction, imaging, spectroscopy, and cryoEM techniques available at the SSRL, LCLS, and cryoEM user facilities. Each section will also include brief talks by early career scientists chosen from submitted abstracts. Awards for best early career oral presentation will be presented after the workshop. If you have questions regarding the symposium, please contact the workshop organizers at fundamentals.ssrl.lcls@gmail.com.

Organizers:  Amy Cordones-Hahn, SLAC; Margaret Doyle, LBNL; Liane Moreau, Washington State University; Linda Vogt, University of Saskatchewan 

LOCATION: SLAC Building 53, Trinity Conference Room 1350-A

Program (PM):

Section 3 - Diffraction/Crystallography

13:00      An overview of X-ray diffraction in theory and in practice, Expert User talk - Prof. Doug Rees, CalTech 

13:30     Structurally informed in situ X-ray diffraction beamline experiments enabled by real time Rietveld analysis, Monty Cosby, SLAC National Accelerator Laboratory

13:50     Time-resolved structural measurements on trimeric Photosystem I from Thermosynechococcus vestitus, Moritz Kretzschmar, Lawrence Berkeley National Laboratory 

14:10     Structural insight into the bifunctional enzyme from the most energy-efficient CO2 fixation cycle, Ebru Destan, Koc University 

14:30      Unveiling the Integrative Dynamic Interrelation between High-Resolution Ambient AspB28 and Cutting-Edge Designer LysB22-AspB28 Insulin Structures through the Synergistic Convergence of SSX vs. HDX-MS/MS: An Exploratory Comparative Study, Esra Ayan, Koc University

14:50     Break

 Section 4 - Imaging

15:10     Introduction to X-ray Imaging, Expert User talk - Dr. Andy Aquila, SLAC National Accelerator Laboratory

15:40     Maximizing FEL coherence with Hermite-Gaussian modes-based machine learning, Avery Hanna, SLAC National Accelerator Laboratory

16:00     Hanbury Brown-Twiss Effect Analysis of the XFEL Transverse Coherence Cross-checked by the Wigner Function Representation, Sophia Zhu, The Harker School

16:20     Towards visualizing the molecular sociology of cardiomyocytes using cryo-electron tomography, Rahel Woldeyes, Stanford University

16:40     Product-stabilized filamentation by human glutamine synthetase tunes activity, Eric Greene, University of California, San Francisco

17:00 Close of afternoon session