Please join in this symposium intended for new and student and postdoc users to learn more about the capabilities and research being conducted at the SLAC User Facilities. This workshop will be accompanied by a new collection of video introductions to the various methods and endstations accessible at SSRL, LCLS, UED, and CryoEM facilities, which can be accessed offline and will grow with additional content each year. During the live Part I and Part II sessions of this symposium, expert PhD scientists will introduce crystallography/diffraction, imaging, spectroscopy, and cryoEM techniques available at the SSRL, LCLS, and cryoEM user facilities. Each section will also include brief talks by early career scientists chosen from submitted abstracts. Awards for best early career oral presentation will be presented after the workshop.

Check out the Fundamentals at SSRL and LCLS YouTube Channel for video introductions to methods at the SLAC User Facilities: https://www.youtube.com/channel/UCoudTEuJWYDFDteBCAuj5hA

      SSRL overview: Prof. Graham George (Univ. of Saskatchewan)

      Stopping time - the emerging science of powerful x-ray lasers: Prof. Uwe Bergmann (U. Wisconsin-Madison)

      Introduction to spectroscopy: Dr. Thomas Kroll (SSRL, SLAC)

      Introduction to gas phase spectroscopy and attosecond science: Dr. James Cryan (LCLS, PULSE Institute, SLAC)

      Introduction to imaging/microscopy at SSRL: Dr. Sharon Bone (SSRL, SLAC)

      Introduction to qRIXS capabilities at LCLS: Dr. Josh Turner (LCLS, SIMES, SLAC)

      Introduction to Crystallography and Scattering capabilities at SSRL: Dr. Chris Tassone (SSRL, SLAC)

      Introduction to serial crystallography: Dr. Art Lyubimov (SSRL, SLAC)

      Introduction to imaging/TXI at LCLS: Dr. Andy Aquila (LCLS, SLAC)

The schedule of live talks can be found below.

Agenda: 

 8:00   Introduction

X-ray Crystallography and Diffraction Section

 8:10  Elspeth Garman (Oxford U) (Expert User)

 8:30  Ebru Destan (KOC U):  Structural insight into the binding mode of Sisomicin derivatives and Gentamicin C2b to the decoding center of the 30S ribosomal subunit

 8:42  Betul Ertem (KOC U):  Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing

 8:54  Tyler Quill (Stanford U): Operando X-Ray Scattering of 3-Terminal Electrochemical Devices Based on Organic Mixed Ionic/Electronic Conductors

 9:06  Break

 9:20  Pranav Kakhandiki (Cornell University/SLAC):  Modes Reconstruction for X-ray Free Electron Lasers using Neural Networks

 9:32  Kenneth Shui (Monta Vista High School):  2D Phase Retrieval for X-ray Free Electron Laser Diffraction Data with Improved Iterative Algorithms

 9:44  Huaiyu Wang (Penn State U):  Terahertz-Field-Driven Collective Dynamics in Polar Skyrmions

10:08  Q&A

10:30  Break

X-ray Imaging Section

10:40  Chunhong 'Chuck' Yoon (SLAC/LCLS) (Expert User)

11:00  Silvia Pandolfi (SLAC/HEDS): XFEL-based time-resolved imaging of void collapse in ICF ablator materials under shock-compression

11:12   Andrew Lee (Stanford U): Dual Role of Hydrogen During Fracture in Iron Revealed using Transmission X-Ray Microscopy

11:24  Sophia Zhu (The Harker School): Hanbury Brown-Twiss Effect described with the Wigner Function

11:36  Q&A

12:00  Break (after the break sign back in to join the afternoon session) 

FYI - 12:00-13:00   Join in the Biology & Life Sciences Poster Session

Link to Poster Hall A -- use Gather platform to meet poster presenters or discuss their research 

X-ray Spectroscopy Section

13:00  Riti Sarangi (SLAC/SSRL) (Expert User)   

13:20   Anup Pradhan Sakhya (U Central Florida):   Observation of Fermi-arcs and Weyl nodes in a new non-centrosymmetric magnetic Weyl semimetal 

13:32  Linxiao Chen (PNNL):  Elucidating the Dynamics of TiO2-Supported Single Metal Atoms and Their Catalytic Consequences with X-Ray Absorption Spectroscopy (XAS)

13:44  Tiffany Slater (U College Cork): The plight of a feather: tracking the degradation of feather corneous beta proteins and identifying their remnants in fossil feathers

13:56  Jianwei Huang (Rice U):  Observation of Three-Dimensional Flat Bands and Dirac Cones in a Pyrochlore Superconductor

14:08  Jackie Wang (UC Santa Cruz):  Diamond fluorescence-based thermometer

14:20  Q&A

14:40  Break

X-ray Spectroscopy Section Continued

14:50  Shinhyo Bang (Washington State U):  A heterogeneous model to extract surface structure of actinide oxide nanoparticles using bulk X-ray absorption spectroscopy

15:02  Jiseop Oh (UC Berkeley):   Intertwined charge density wave in a magnetic kagome metal FeGe

15:14  Kiley Mayford (UC Santa Cruz):   Environment Around Sn and Ge Doped Hematite: Substitution vs. Precipitation in Relation to Total Dopant Concentration

15:26  Hyeongtaek Lim (Stanford U):   Identifying excited state character of Ni-based H2 evolution catalyst using ultrafast X-ray absorption spectroscopy

15:38  Andrey Poletayev (Stanford U):   Probing Ionic Conduction with Terahertz Pump-Probe Spectroscopy

15:50  Lorena Grundy (UC Berkeley):   Detection of New Mechanisms for the Limiting Current Using in situ X-Ray Absorption and Small-Angle X-Ray Scattering

16:02  Q&A

16:20  Break

CryoEM Section

16:30  Wah Chiu (Stanford/SLAC/SSRL) (Expert User)

16:50  Eric Greene (UCSF): Supramolecular organization of glutamine synthetase along reaction coordinate

17:02  David Boyer (UCLA):  Structure Determination of Amyloid-Beta Oligomers

17:15  Q&A

Organizers:

Isabel Bogacz, Lawrence Berkeley National Laboratory

Amy Cordones-Hahn, Stanford University/PULSE/SLAC

Ailiena Maggiolo, California Institute of Technology

Liane Moreau, Washington State University, liane.moreau@wsu.edu

Linda Vogt, University of Saskatchewan

Invited Speakers: 

Elspeth Garman (Oxford U) 

Ebru Destan (KOC U)

Betul Ertem (KOC U)

Tyler Quill (Stanford U)

Pranav Kakhandiki (SLAC)

Kenneth Shui (Monta Vista High School)

Huaiyu Wang (Penn State U)

Chunhong 'Chuck' Yoon (SLAC/LCLS)

Silvia Pandolfi (SLAC/HEDS)

Andrew Lee (Stanford U)

Sophia Zhu (The Harker School)

Riti Sarangi (SLAC/SSRL)

Anup Pradhan Sakhya (U Central Florida)

Linxiao Chen (PNNL)

Tiffany Slater (U College Cork)

Jianwei Huang (Rice U)

Jackie Wang (UC Santa Cruz)

Shinhyo Bang (Washington State U)

Jiseop Oh (UC Berkeley)

Kiley Mayford (UC Santa Cruz)

Hyeongtaek Lim (Stanford U)

Andrey Poletayev (Stanford U)

Lorena Grundy (UC Berkeley)

Wah Chiu (Stanford/SLAC/SSRL) 

Eric Greene (UCSF)

David Boyer (UCLA)