Lupus Nephritis: The ACR Guideline in Practice

The American College of Rheumatology has released an updated, comprehensive lupus nephritis (LN) practice guideline focused on enhancing the screening, monitoring and treatment of kidney involvement in systemic lupus erythematosus (SLE). The recommendations in this guideline support clinicians in achieving timely diagnosis, appropriate risk stratification and evidence-based management of LN to help prevent irreversible kidney damage and improve long-term outcomes for patients with SLE.

Learning objectives:

• Understand how the ACR LN guidelines were developed, including the GRADE process, patient input, and decision-making by the voting panel.
• Apply ACR recommendations for screening and monitoring LN, including routine urinalysis, proteinuria quantification, serologic markers, and timely kidney biopsy when indicated.
• Implement evidence-based therapies for managing LN.
• Recognize and manage progressive or refractory LN, including escalation of therapy and reassessment with repeat biopsy when appropriate.
• Coordinate multidisciplinary care (rheumatology + nephrology) to improve outcomes, reduce toxicity, and support long-term patient-centered management.

Target audience:

This webinar is designed for healthcare professionals involved in managing adult patients with SLE, including rheumatologists, nephrologists, internists, nurse practitioners, physician assistants, and other clinicians providing care to individuals at risk for or diagnosed with lupus nephritis.