Predicting PFAS Tumorigenicity With Cell Communication Bioassays

Join us for an exclusive cutting-edge webinar exploring how the disruption of gap junctional intercellular communication (GJIC) is not only an essential and early step in carcinogenesis, but also a critical mechanism underlying a range of adverse health effects. GJIC is fundamental to cellular signaling and gene expression at the tissue level—its interruption is a hallmark of abnormal cell proliferation seen in cancer and other diseases.

This program will introduce both in vitro and in vivo bioassays that measure GJIC, demonstrating their value in assessing the biosafety of pharmaceuticals, industrial by-products, environmental pollutants, and food safety. Special focus will be given to the effects of per- and polyfluoroalkyl substances (PFAS) on GJIC, and the promising potential of natural products—whether food or supplement-based—to prevent or reverse PFAS-induced harm.

Why This Matters Now: 

PFAS are at the forefront of environmental, toxicological, and oncological research due to their persistence, bioaccumulation, and links to cancer and other health risks. Understanding their mechanisms of action and strategies for mitigation is critical for scientists, regulators, and innovators alike.

Three Key Take-Home Messages

• Gap Junction Bioassays: The New Frontier in Toxicology
  Discover why gap junction bioassays are rapidly becoming essential tools for toxicological assessment of PFAS and other emerging contaminants. Their relevance in high-throughput systems opens new possibilities for large-scale screening and regulatory science.
• Predictive Power: Structure-Activity Relationships of PFAS
  Learn how the latest research reveals structure-activity relationships in PFAS, enabling predictive models of toxicity. This knowledge empowers scientists to anticipate risks and design safer chemicals.
• Hope for Mitigation: Nutrition and Supplements as Interventions
  Explore groundbreaking findings on how natural products—both foods and supplements—may help mitigate the toxic effects of PFAS, offering new avenues for improving health outcomes in exposed populations.

Who should attend?

This premium digital event is designed for: 

• R&D Project Managers
• R&D Scientists
• Research Professors
• Biomedical Engineers
• Toxicologists
• Environmental Scientists
• Environmental Regulators
• Food Scientists
• Biochemists
• Molecular Biologists

What's Included:

• Access to the live broadcast on Thursday October 30, 2025
• The opportunity to ask questions directly to the speaker (on camera or by chat, your preference!)
• A certificate of attendance
• On-demand access to the recording for 1 year