This session highlights the recent use of cryoEM structure determination of SARS-COVID-2 related macromolecules. Speakers will cover structures of different molecular components of the virus and the cellular interacting partners. Some of talks will describe the impact of the structural results on vaccine and drug developments.
*The S2C2 is supported by the National Institutes of Health Common Fund Transformative High Resolution Cryo-Electron Microscopy program.
The session presentations will be broadcast through a Zoom webinar which can be accessed by the 'Join Broadcast' button that will be accessible on this page at the start of the 8:00 am session. Webinar Passcode: 987654
Organizers:
Wah Chiu, Stanford University
Agenda:
8:00 AM Structural studies of the SARS-CoV Spike Glycoprotein David Veesler, University of Washington, Seattle
8:45 AM The use of cryoEM structural information to advance SARS2-CoV-2 biology and therapy” David Stuart, Oxford University and Diamond Light Source
9:30 AM Structure of replicating SARS-COV-2 polymerase Goran Kokic, Max Planck Institute for Biophysical Chemistry, Göttingen
10:15 AM BREAK
10:45 AM Antibodies against Emerging Viral Disease Erica Ollmann Saphire, La Jolla Institute for Immunology
11:30 AM CryoEM of previously unsolvable RNA structures including coronavirus genome elements Rhiju Das, Stanford University
12:15 AM Targeting Vacuolar H+-ATPase for Antiviral Therapy Stephan Wilkens, SUNY Upstate Medical University, Syracuse